CO129-468 - Governor Sir Stubbs - 1921 [6-8] — Page 106

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oravling age in sentas: with a person suffering from ope tuberculosis,er we fi living in a reen previously sssuşied by much a persen, are enormous. The danger of Infection from tuberculous members of a family is not,according to the weight of evidence new available,due to the mere "tandeney to infection," er even to the increased probability of infection per se, but is to be ascribed to the probable large sise and frequency of the infesting doses. It has been showı experimentally that mall repeated infections may be pretestive,but large ones overwhelmn. Thus is explained the apparent antagonim of Calmette'a and of Bryant's experinets. The former have already bom mentioned with reformes to single er reported infection of cattle, either directly or by keeping them in emtaet with tuberculeus animals. Bryant, after injeåting guinea-pigs with a mall number (8) of bacilli daily for a time and then every three days for a period of four months,found lesions indicativo

of great resistance.

The sonditions in Rangkang,sa has bem pointed out,are snalegous to the experimente of Calmette. It is needless to labour this point further, but in conclusion xestión may be made of Theobald Budth's statement in the Journal of the Amerism Medical Association: "The resistenes of the tuberculeus animal to superinfestion is readily breken dem by slightly inoressed dosage, and is successful only when very minute

deses some inte play."

Bubsequent papers on the subjects of the perials of entry of the basillus and on the post-mortem findings in eases in Hengkeng substantiato in detail the previous statements. If time allows it is my intention to tas up later the ezanin tion of the dust,ete,,in the resus of the poorer eluasen to see what proportion of them astually harbour the tuberele bacilius. Begring the above points in mind we may,

in conclusion of this section,put forward me or two suggestions which arise out of these investigations, directed towards the mitigation of the scourge,for,as already statai, tubareulosis must be regarded prominently as a preventable disease.

The bread study of the sendition servos to show that more academic and experimen- tal knowledge will go but a little way in elucidation of the various and complex problems which the disease presets, As already mentioned the prevalence of tuber- pulosis is closely commested with social and coenomic senditions—evererowding and slums, poverty, insanitation and squaler, With regard to evercrowding little,if any. thing,san be done; the space available is limited and the population is relatively large and is increasing, The question reduses itself,for practical purposes, to the Finding of a remedy for the sitting habit in the first plass, The use of feed